EFSD/Novo Nordisk Programme for Diabetes Research in Europe

2023

Alastair Kerr: Karolinska Institute - Huddinge, Sweden
A missing link (RNA) in fat breakdown regulation

Fredrik Bäckhed: University of Gothenburg - Sweden
Gut microbial regulation of colonic GLP-1 production and effects on gut physiology

Jurga Laurencikiene: Karolinska Institute - Huddinge, Sweden
Type 2 diabetes and adipose tissue morphology: dual role and sex-specificity of the immune component

Luis Rodrigo Cataldo: Lund University - Malmö, Sweden
EPDR1 – a novel human batokine regulating beta cell function and glucose homeostasis

Zachary Gerhart-Hines: University of Copenhagen - Denmark
Nocturnal thermogenesis as a driver of metabolic health and defense against weight gain in humans

2022

Sonia Fernandez Veledo: Pere Virgili Health Research Institute - Tarragona, Spain
NEUROinflammatory role of the succinate/SUCNR1 axis in obesity-related DIAbetes (NEURO_DIA)

Filip Knop: University of Copenhagen - Denmark
Separate and combined extrapancreatic effects of the incretin hormones

Vito Lampasona: Vita-Salute San Raffaele University - Milan, Italy
Insulin granules proteins: novel autoimmune targets and biomarkers in type 1 diabetes

Gil Leibowitz: Hadassah-Hebrew University Medical Center - Jerusalem, Israel
Fructose is central in diabetic kidney disease and mediates the protective effects of SGLT2 inhibitors

Peter van Endert: INSERM U1151 - Paris, France
Tolerogenic nanoparticles inducing regulatory B and T lymphocytes for therapy of autoimmune diabetes

2021

Elise Dalmas: INSERM U1138 - Paris, France
CD200: a novel immune rheostat of pancreatic islets

Franck Oury: INSERM U1151 - Paris, France
Investigation of a PTHrp/autophagy axis in the control of metabolism and as a new therapeutic target

Kirsty Spalding: Karolinska Institutet - Stockholm, Sweden
Cell regeneration in the human kidney in health and diabetic kidney disease

Nicolas Venteclef: INSERM U1138 - Paris, France
Impact of KMD6B dependent-epigenetic reprogramming of adipose tissue macrophage plasticity in type 2 diabetes

Harriet Wallberg-Henriksson: Karolinska Institutet - Stockholm, Sweden
Exercise response and circadian rhythm for type 2 diabetes prevention and management

Juleen Zierath: Karolinska Institutet - Stockholm, Sweden
Role of energy sensing pathways in the circadian control of metabolism

2020

Charna Dibner: University of Geneva - Switzerland
Bridging the gap between disrupted circadian clocks and human islet function upon type 2 diabetes

Mario Galgani: Istituto per l'Endocrinologia e l'Oncologia Sperimentale "G.Salvatore" - Naples, Italy
TR3-56 cells: the missing piece in the puzzle of type 1 diabetes progression

Mariana Igoillo-Esteve: Université Libre de Bruxelles - Belgium
tRNA hypomethylation and fragmentation, a novel mechanism of pancreatic beta cell demise in diabetes

Susanne Keipert: Stockholm University - Sweden
The impact of FGF21 sensitivity on metabolic syndrome progression

Anja Zeigerer: Helmholtz Center Munich - Neuherberg, Germany
Identification of the novel role of Vps33b in blood glucose control

2019

Christian Boitard: INSERM - France
Identification of DQ8-restricted CD4+ T-cell responses to hPPI and T-cell assays in type 1 diabetes patients

Georgia Fousteri: San Raffaele Hospital - Italy
Engineered treg cell therapy for pancreatic islet transplantation

Dominique Langin: Obesity Research Laboratory - France
Inhibition of HSL/ChREBP interaction to prevent type 2 diabetes

Vanessa Lavallard: University of Geneva - Switzerland
Role of beta cells in the regulation of glucagon secretion

Olivia Lenoir: INSERM - France
Autophagy as protective mechanism in diabetic nephropathy

Margit Mahlapuu: Inst. of Chemistry and Molecular Biology - Sweden
Molecular mechanisms regulating ectopic lipid deposition and insulin resistance

Giuseppe Pugliese: La Sapienza University - Italy
Effect of exercise training on bone quality and strength in individuals with type 2 diabetes

Juleen R. Zierath: Karolinska Institutet - Sweden
Diacylglycerol Kinase d in the regulation of glucose metabolism and energy homeostasis

Antonio Zorzano: IRB Barcelona - Spain
Mitochondrial dynamics as a target for the treatment of type 2 diabetes and its complications

2018

Hadi Al-Hasani: DDZ, Heinrich Heine University - Düsseldorf, Germany
Novel pathways for TBC1D4 in controlling exercise-mediated improvements of systemic insulin sensitivity

Luc Baeyens: Free University Brussels - Belgium
Pregnancy signals affect human beta cell replication and function

Craig Beall: University of Exeter - UK
The role of astroglial mitochondrial dysfunction in altered neuron-astrocyte signalling during hypoglycaemia in diabetes

Françoise Carlotti: Leiden University Medical Center - Netherlands
Exploring novel mechanisms of beta cell failure in type 2 diabetes

Ulf Eriksson: Karolinska Institute - Stockholm, Sweden
VEGF-B mediated lipotoxicity as a determinant for the progression of diabetic kidney disease

Johan Jonker: University Medical Center Groningen - Netherlands
Role of the adaptive unfolded protein response in the metabolic effects of Fibroblast Growth Factor 1

Olle Korsgren: Uppsala University Hospital - Sweden
Quantitative PET imaging of the immune system in type 1 diabetes

Romeo Ricci: CERBM-GIE - Illkirch, France
Lysosomal pathways: A chemical screening approach to find new drugs improving beta cell health

Eran Segal: Weizmann Institute of Science - Rehovot, Israel
Prediction of blood glucose level in type 1 diabetes patients using deep artificial neural networks

Coert Zuurbier: Academic Medical Center - Amsterdam, Netherlands
Direct cardiac effects of SGLT2 inhibitor on diabetic cardiac function and heart failure independent of SGLT2 receptors

2017

Karine Clément: Pitié Salpetrière Hospital - Paris, France
Controlling fate of adipose tissue-derived progenitors to improve obesity-related insulin resistance

Fiona Gribble: University of Cambridge - UK
Impact of bypass surgery on glucose metabolism in lean adults

Mariana Igoillo-Esteve: Free University Brussels - Belgium
tRNA hypomodifications: a novel pathogenic mechanism of diabetes

Filip Knop: University of Copenhagen - Denmark
Anatomical and physiological delineation of gut-derived glucagon in man

Limor Landsman: Tel Aviv University - Israel
Promoting adult beta cell replication by neonatal pericytic factors

Rashmi Prasad: Lund University - Malmö, Sweden
Dissecting parent-of-origin effects in type 2 diabetes and identification of novel biomarkers for pancreatic development

Anders Tengholm: Uppsala University - Sweden
Alpha cell signalling in glucose-regulated glucagon secretion

Rebecca Wall: Örebro University - Sweden
Butyrogenic fibres as a potential strategy for the prevention of type 2 diabetes                                              

Christodoulos Xinaris: Mario Negri Institute - Bergamo, Italy
Podocyte foetal reprogramming in diabetic nephropathy: the key role of thyroid hormone receptors

2016

Peter Carmeliet: Flanders Institute for Biotechnology - Zwijnaarde, Belgium
Control of glycaemia in health and diabetes by production of glucose from the endothelium

Herminia González-Navarro: Institute of Health Research - Valencia, Spain
Role of the cytokine LIGHT(TNFSF14) in the development of insulin resistance and fatty liver disease

Margit Mahlapuu: University of Gothenburg - Sweden
Molecular mechanisms regulating ectopic lipid deposition and insulin resistance

Luca Scorrano: Venetian Institute of Molecular Medicine - Padua, Italy
The role of the mitochondria-shaping protein Opa1 in fat browning and insulin sensitivity

Rudi Vennekens: Catholic University Leuven - Belgium
Properties and therapeutic potential of the TRPM5 ion channel in human pancreatic beta cells

2015

Romain Barrès: University of Copenhagen - Denmark
Role of the gut microbiome on the epigenome of intestinal cells after bariatric surgery

Peter Carmeliet: Flanders Institute for Biotechnology - Zwijnaarde, Belgium
Profiling of metabolism in diabetic endothelial cells

Birgit Gustafson: University of Gothenburg - Sweden
Regulation of human brown/beige adipogenesis by the BMP antagonist GREM1

Jens Juul Holst: University of Copenhagen - Denmark
Involvement of glucose-dependent insulinotropic polypeptide in human physiology and pathophysiology - receptor antagonist studies in humans

Johan Jonker: University Medical Center Groningen - The Netherlands
Role of nuclear receptor TR4 and co-repressor Jazf1 in the regulation of glucose homeostasis and development of T2D

Claudia Miele: National Council of Research - Naples, Italy
Impaired angiogenesis in diabetes: unravelling the role of glyoxalase 1 and methylglyoxal

Bart Staels: University Lille - France
Role of the nuclear receptor FXR in obesity-induced adipose tissue inflammation

2014

Lena Alexopoulou: University Aix-Marseille - France
Contribution of TLR8 and TLR7 in obesity-associated insulin resistance and diabetes

Harry Heimberg: Free University Brussels - Belgium
Cytokine-induced neogenesis of beta cells by reprogramming of exocrine cells of the pancreas as a therapy for diabetes

Francesco Cosentino: Karolinska Institute - Stockholm, Sweden
Epigenetic changes and endothelial insulin resistance: role of methyltransferase Set7

Sandra Guilmeau: Paris Descartes University - France
Contribution of carbohydrate metabolism via ChREBP to intestinal GLP1 production and glucose homeostasis

Federico Mayo: Autonomous University Madrid - Spain
Novel molecular mechanisms linking GRK2 as a new therapeutic target in diabetes

Susan Wong: Cardiff University - UK
Modulation of insulin-specific T cell receptor repertoire by the gut microbiome

2013

Riccardo Bonadonna: University of Verona - Italy
Meal glucose regulation in patients with type 1 diabetes on insulin pump therapy: towards a better understanding of the glucose-insulin system

Claudia P. Cooman: Leiden University Medical Center - The Netherlands
Targeting brown adipose tissue activity as therapy for obesity and diabetes resulting from circadian dysregulation

Jorge Ferrer: Imperial College London - UK
Epigenetic regulation of beta cell development and growth 

Olga Gorni: University of Zagreb - Croatia
Protein fucosylation in diagnosis of maturity onset diabetes of the young 

Francesco Villarroy: University of Barcelona - Spain
Identification of novel endocrine factors secreted by brown fat (batokines) with anti-diabetic action

2012

Pontus Boström: Karolinska Institute - Stockholm, Sweden
Irisin - a novel myokine protective against metabolic disease

Joan Guinovart: Institute for Research in Biomedicine - Barcelona, Spain
The role of glycogen metabolism in the pancreatic beta cell

Olle Korsgren: Uppsala University Hospital - Sweden
Imaging of the human endocrine pancreas

Margit Mahlapuu: University of Gothenburg - Sweden
Regulation of metabolic and inflammatory balance in liver and skeletal muscle

Romano Regazzi: University of Lausanne - Switzerland
Induction of beta cell mass expansion by modulation of the level of specific microRNAs

Solomon Tesfaye: Royal Hallamshire Hospital - Sheffield, UK
The microvascular perfusion characteristics of the pain processing areas of the brain in painful diabetic neuropathy

Erik Toonen: Radboud University - Nijmegen, The Netherlands
Proteinase 3: a new link between inflammation, obesity and type 2 diabetes

2011

Henning Beck-Nielsen: Odense University Hospital - Denmark
Enviromental versus genetic and epigenetic influences on growth, metabolism and cognitive function in offspring of mothers with type 1 diabetes

Miriam Cnop: Free University of Brussels - Belgium
The DNA methylation landscape of type 2 diabetes

Michael Elkin: Hadassah-Hebrew University - Jerusalem, Israel
Heparanase in diabetic nephropathy: mode of action and therapeutic implications

Luis Graca: University of Lisbon - Portugal
Cellular therapy to induce local immune suppression in islet transplantation

Anders Rosengren: Lund University - Malmö, Sweden
Drug repositioning in type 2 diabetes - clinical trials in specific patient sub-groups

Hubert Vidal: South Lyon Medical Facility - France
Food pollutants and maternal obesity: impact on metabolism and inflammatory status in offspring

Suvi Virtanen: National Institute for Health and Welfare - Helsinki, Finland
Early nutrition in the development of pre-type 1 diabetes: a prospective cohort study

2010

Luc Bouwens: Free University Brussels - Belgium
Transdifferentiation of human exocrine acinar cells to endocrine beta cells by STAT3 and MAPK signalling

Per-Ola Carlsson: Uppsala University - Sweden
Bioengineering pancreatic islets for transplantation purposes in type 1 diabetes

Malin Flodström-Tullberg: Karolinska Institute - Stockholm, Sweden
Studies on the role of passively acquired immunity and the intestine in regulating enterovirus-induced diabetes

Anthony Gavalas: Academy of Athens - Greece
Signalling pathways in the conversion of pancreas progenitors to beta cells

Jarna Hannukainen: Turku University - Finland
The prescription for metabolic and cardiovascular diseases: high-intensity, short-time interval training

Leif Jansson: Uppsala University - Sweden
Interactions between islet vascular and endocrine cells: implications for the pathogenesis of diabetes

Josep Jimenez-Chillaron: Sant Joan de Deu Foundation - Barcelona, Spain
Mouse model for the study of non-genomic inheritance of diabetes

Richard Leslie: Queen Mary University of London - UK
DNA methylation signature in immune cells in type 1 diabetes: a study of identical twins

Cedric Moro: Rangueil Hospital - Toulouse, France
Lipases regulation of fatty acid metabolism and insulin sensitivity in skeletal muscle

Tina Vilsbøll: Copenhagen University - Denmark
The role of intact vagal innervation for the GLP-1-induced insulin secretion